Can multiple sclerosis cause loss of use of hands?

See answer below. Absolutely. The spectrum of MS symptoms is wide and anything can be seen with MS depending on where CNS lesions are located. On occasions, someone may lose function in their hands from MS whether it be secondary to weakness, loss of proprioception or simply from loss of sensation.
Comorbidity. Have encountered comorbidity of carpal tunnel syndrome, and also, seen a few pts with low b-12 levels, but these are merely additional issues superimposed on ms. However, on occasion, may pay to consider alternative causes for some hand issues.