2 doctors weighed in:
How does caffeine affect the results of thallium myocardial perfusion scan?
2 doctors weighed in

Dr. Thomas Heston
Family Medicine
In brief: False-negative
Caffeine can interfere with vasodilator pharmacologic stress testing, so your thallium myocardial perfusion scan might be normal even though you have cardiac perfusion problems.
Best to hold caffeine for 48 hours prior to the test. You don't always know ahead of time whether an exercise stress test will work, so it is recommended that everyone hold caffeine for a couple of days prior to the study.

In brief: False-negative
Caffeine can interfere with vasodilator pharmacologic stress testing, so your thallium myocardial perfusion scan might be normal even though you have cardiac perfusion problems.
Best to hold caffeine for 48 hours prior to the test. You don't always know ahead of time whether an exercise stress test will work, so it is recommended that everyone hold caffeine for a couple of days prior to the study.
Dr. Thomas Heston
Dr. Thomas Heston
Thank
Dr. Thomas Heston
Family Medicine
In brief: Sometimes not at all
Caffeine can interfere with the pharmacologic stress test used in conjunction with thallium myocardial perfusion scanning.
It blocks the effect of the stress agent (e.g. Dipyridamole) which makes the thallium stress-rest perfusion scan less accurate. If you perform exercise stress and achieve your target heart rate, caffeine shouldn't affect the scan much if at all.

In brief: Sometimes not at all
Caffeine can interfere with the pharmacologic stress test used in conjunction with thallium myocardial perfusion scanning.
It blocks the effect of the stress agent (e.g. Dipyridamole) which makes the thallium stress-rest perfusion scan less accurate. If you perform exercise stress and achieve your target heart rate, caffeine shouldn't affect the scan much if at all.
Dr. Thomas Heston
Dr. Thomas Heston
Thank
Dr. Samuel Hahn
Internal Medicine - Cardiology
In brief: Not usually
Caffeine in the usual dietary dose won't affect an exercise stress test with thallium imaging, but if you ingest caffeine recently you cannot have a stress test with pharmacologic stress using Persantine (dipyridamole), Adenosine or Lexiscan because the caffeine interferes with the metabolism of those agents.

In brief: Not usually
Caffeine in the usual dietary dose won't affect an exercise stress test with thallium imaging, but if you ingest caffeine recently you cannot have a stress test with pharmacologic stress using Persantine (dipyridamole), Adenosine or Lexiscan because the caffeine interferes with the metabolism of those agents.
Dr. Samuel Hahn
Dr. Samuel Hahn
Thank
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