8 doctors weighed in:

How to prevent further hereditary breast cancer?

8 doctors weighed in
Dr. Barry Rosen
Surgery
5 doctors agree

In brief: 3 options, currently

Women who are brca(+) have a 50-80% lifetime risk of breast cancer.
The 3 best options currently are: 1-prophylactic bilateral mastectomy (+/-reconstruction); 2-chemoprevention with tamoxifen, which may reduce the risk of cancer by 25-50%, and; 3-close surveillance evaluation, including regular breast mri. Unfortunately, none of these options are ideal-hopefully a better option is on the horizon.

In brief: 3 options, currently

Women who are brca(+) have a 50-80% lifetime risk of breast cancer.
The 3 best options currently are: 1-prophylactic bilateral mastectomy (+/-reconstruction); 2-chemoprevention with tamoxifen, which may reduce the risk of cancer by 25-50%, and; 3-close surveillance evaluation, including regular breast mri. Unfortunately, none of these options are ideal-hopefully a better option is on the horizon.
Dr. Barry Rosen
Dr. Barry Rosen
Thank
1 comment
Dr. Benjamin Kim
BRCA+ women undergoing prophylactic mastectomy should consider bilateral oophorectomy to reduce ovarian cancer risk.
Dr. Gurmukh Singh
Pathology
1 doctor agrees

In brief: Difficult to say

Prevention of inherited disorders involves reproductive decisions and at this time there are no clear cut guidelines specific to breast cancer.
A general statement could be made that people with known, inherited and heritable genetic defects may consider limiting their reproduction. Further developments in science may allow targeted exclusion of gametes with defective genes.

In brief: Difficult to say

Prevention of inherited disorders involves reproductive decisions and at this time there are no clear cut guidelines specific to breast cancer.
A general statement could be made that people with known, inherited and heritable genetic defects may consider limiting their reproduction. Further developments in science may allow targeted exclusion of gametes with defective genes.
Dr. Gurmukh Singh
Dr. Gurmukh Singh
Thank
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