Adolph's, Not Lupin
If you are referring to the plant, lupin, I have not seen any scientific data published.
After the stinger is carefully removed (with the side of a credit card) and the skin is thoroughly cleansed, apply adolph's meat tenderizer. It neutralizes the venom of the bee sting
. Or dissolve the meat tenderizer in water and soak a cotton ball in the solution. Apply to the sting for 10 to 15 minutes.