12 doctors weighed in:
What medications treat dupuytren's disease?
12 doctors weighed in

Dr. Robert Coats II
Orthopedic Surgery
2 doctors agree
In brief: Only one
Dupuytren's contracture is a genetically mediated fibroproliferative disorder, which causes contractures of the fingers.
The only fda approved medical treatment for dupuytren's contracture with a palpable cord is xiaflex (collagenase clostridium histolyticum). Xiaflex (collagenase clostridium histolyticum) is a collagenase, which is an enzyme that breaks down collagen. Collagen build-up leads to contracture. Once dissolved, the finger can be straightened in the office.

In brief: Only one
Dupuytren's contracture is a genetically mediated fibroproliferative disorder, which causes contractures of the fingers.
The only fda approved medical treatment for dupuytren's contracture with a palpable cord is xiaflex (collagenase clostridium histolyticum). Xiaflex (collagenase clostridium histolyticum) is a collagenase, which is an enzyme that breaks down collagen. Collagen build-up leads to contracture. Once dissolved, the finger can be straightened in the office.
Dr. Robert Coats II
Dr. Robert Coats II
Thank
1 comment
Dr. Jeffrey Wint
https://www.facebook.com/pages/Dupuytrens-Disease-New-treatment-Updates/147337105335050?ref=hl
Dr. Gary Pess
Surgery - Hand Surgery
1 doctor agrees
In brief: Xiaflex (collagenase clostridium histolyticum)
Xiaflex (collagenase clostridium histolyticum) is the only fda drug approved and found to be successful in treating dupuytren's contracture.

In brief: Xiaflex (collagenase clostridium histolyticum)
Xiaflex (collagenase clostridium histolyticum) is the only fda drug approved and found to be successful in treating dupuytren's contracture.
Dr. Gary Pess
Dr. Gary Pess
Thank
Dr. Matthew Welsch
Surgery - Hand Surgery
1 doctor agrees
In brief: No oral medications
No oral medications affect dupuytrens, but there is an injectable "medication" that acts to dissolve a portion of the dupuytrens cord.
Best to discuss this medication with a hand specialist.J.

In brief: No oral medications
No oral medications affect dupuytrens, but there is an injectable "medication" that acts to dissolve a portion of the dupuytrens cord.
Best to discuss this medication with a hand specialist.J.
Dr. Matthew Welsch
Dr. Matthew Welsch
Thank
Dr. Teddy Atik
Surgery - Hand Surgery
In brief: Xiaflex (collagenase clostridium histolyticum)
Xiaflex (collagenase clostridium histolyticum) is a medication injected into the cord which ruptures it, releasing the contracture but it does recur. There is no cure

In brief: Xiaflex (collagenase clostridium histolyticum)
Xiaflex (collagenase clostridium histolyticum) is a medication injected into the cord which ruptures it, releasing the contracture but it does recur. There is no cure
Dr. Teddy Atik
Dr. Teddy Atik
Thank
In brief: Alternative to
Xiaflex (collagenase clostridium histolyticum) is the paris procedure with kenalog.
Works great. A hand surgeon colleague of mine taught me this and I have adapted it to the foot.

In brief: Alternative to
Xiaflex (collagenase clostridium histolyticum) is the paris procedure with kenalog.
Works great. A hand surgeon colleague of mine taught me this and I have adapted it to the foot.
Dr. Eugene Batelli
Dr. Eugene Batelli
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Dr. Mark Ciaglia
Surgery - Hand Surgery
In brief: Xiaflex (collagenase clostridium histolyticum)
Xiaflex (collagenase clostridium histolyticum) is a medication that is injected into the dupuytrens cord in the hand to dissolve the collagen and release the contracture.
It is been out for a few years and has had promising results as an alternative to open surgical treatments.

In brief: Xiaflex (collagenase clostridium histolyticum)
Xiaflex (collagenase clostridium histolyticum) is a medication that is injected into the dupuytrens cord in the hand to dissolve the collagen and release the contracture.
It is been out for a few years and has had promising results as an alternative to open surgical treatments.
Dr. Mark Ciaglia
Dr. Mark Ciaglia
Thank
Dr. Jeffrey Wint
Surgery - Hand Surgery
Dr. F. Thomas Kaplan
Surgery - Hand Surgery
In brief: None
Dupuytren's disease is not helped by medication.
Unfortunately we do not know of anything that will stop or prevent the disease. There is a new treatment for dupuytren's where an enzyme, collagenase, is injected into the abnormal tissue to dissolve and weaken it. A hand surgeon can give you more information about it, or visit www.Xiaflex.Com.

In brief: None
Dupuytren's disease is not helped by medication.
Unfortunately we do not know of anything that will stop or prevent the disease. There is a new treatment for dupuytren's where an enzyme, collagenase, is injected into the abnormal tissue to dissolve and weaken it. A hand surgeon can give you more information about it, or visit www.Xiaflex.Com.
Dr. F. Thomas Kaplan
Dr. F. Thomas Kaplan
Thank
Dr. Robert Gluck
Surgery - Hand Surgery
In brief: Collagenase
Marketed as xiaflex, (collagenase clostridium histolyticum) this is a form of Collagenase that gets injected into dupuytrens cords in the palm of the hand.
At a second stage the following day, once the cord is weakened by the collagenase, the cord can be disrupted. This is a fairly straightforward office procedure and has certain advantages over surgery in many situations. See more at www.Myhandhealth.Com, click on duputytrens/xiaflex.

In brief: Collagenase
Marketed as xiaflex, (collagenase clostridium histolyticum) this is a form of Collagenase that gets injected into dupuytrens cords in the palm of the hand.
At a second stage the following day, once the cord is weakened by the collagenase, the cord can be disrupted. This is a fairly straightforward office procedure and has certain advantages over surgery in many situations. See more at www.Myhandhealth.Com, click on duputytrens/xiaflex.
Dr. Robert Gluck
Dr. Robert Gluck
Thank
1 comment
Dr. Jeffrey Wint
https://www.facebook.com/pages/Dupuytrens-Disease-New-treatment-Updates/147337105335050?ref=hl
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