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How is holoprosencephaly malformation complex caused?

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Dr. Nikolaos Zacharias
Obstetrics & Gynecology - Maternal Fetal Medicine

In brief: Neuronal migration.

Holoprosencephaly is a developmental anomaly typically found in trisomy 13 (patau syndrome) and associated with neuronal migration anomalies resulting in fusion of the cerebral ventricles and hemispheres.

In brief: Neuronal migration.

Holoprosencephaly is a developmental anomaly typically found in trisomy 13 (patau syndrome) and associated with neuronal migration anomalies resulting in fusion of the cerebral ventricles and hemispheres.
Dr. Nikolaos Zacharias
Dr. Nikolaos Zacharias
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