Is there a possibly to get serious complications from acid reflux?

Like cancer...Yes! Acid reflux, when chronic, can lead to permanent changes in the esophagus with scarring (strictures), & precancerous tissue (barrett's) that progresses to esophageal malignancy. Chronic exposure of vocal cords to refluxed material can promote asthma, & even laryngeal cancer. Other concerns include eroded teeth, chronic sinusitis, not to mention profoundly altered quality of life for sufferers.