6 doctors weighed in:

Will pulmonary hypertension run in families?

6 doctors weighed in
Dr. Mark Avdalovic
Internal Medicine - Pulmonary Critical Care
2 doctors agree

In brief: Potentially

Potentially but is is very rare.
Likely less than 1 in a million. There is a mutation that is frequent among patient with unexplained pulmonary htn, formally termed idiopathic pulmonary arterial hypertension. Current research is focused on identifying potential target of therapy that involve the genes related to familial pulmonary htn.

In brief: Potentially

Potentially but is is very rare.
Likely less than 1 in a million. There is a mutation that is frequent among patient with unexplained pulmonary htn, formally termed idiopathic pulmonary arterial hypertension. Current research is focused on identifying potential target of therapy that involve the genes related to familial pulmonary htn.
Dr. Mark Avdalovic
Dr. Mark Avdalovic
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Dr. Donald Elton
Internal Medicine - Pulmonology
1 doctor agrees

In brief: Sometimes

There are some inherited forms of pulmonary hypertension that are very rare but pulmonary hypertension can result from certain collagen vascular diseases like scleroderma and sometimes these run in families.

In brief: Sometimes

There are some inherited forms of pulmonary hypertension that are very rare but pulmonary hypertension can result from certain collagen vascular diseases like scleroderma and sometimes these run in families.
Dr. Donald Elton
Dr. Donald Elton
Thank
Dr. Charles Burger
Internal Medicine - Pulmonology

In brief: PAH may be inherited

Up to 5% of patients with pulmonary arterial hypertension (pah) may have a genetic or heritable cause.
Research studies have identified a genetic abnormality affecting bone morphogenetic protein receptor 2 (bmpr2) that appears to predispose a patient to pah. Fortunately, even if an individual inherits the abnormal gene, the likelihood of developing pah is only 1 in 5.

In brief: PAH may be inherited

Up to 5% of patients with pulmonary arterial hypertension (pah) may have a genetic or heritable cause.
Research studies have identified a genetic abnormality affecting bone morphogenetic protein receptor 2 (bmpr2) that appears to predispose a patient to pah. Fortunately, even if an individual inherits the abnormal gene, the likelihood of developing pah is only 1 in 5.
Dr. Charles Burger
Dr. Charles Burger
Thank
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