Who would need a urine catecholamine fractionation?

Possible tumor. Urine catecholamines are separated into dopamine, epinephrine, norepinephrine, vma, and dopa, among others. Each of these metabolites are differently expressed by certain tumors, often in the adrenal gland, or sometimes in other sites. This gives a guide to where to test further, or what else may be giving rise to the symptoms (often high blood pressure, heart beat abnormalities, etc).