6 doctors weighed in:

Why would a person need a serum apolipoprotein b measurement?

6 doctors weighed in
Dr. Gurmukh Singh
Pathology
2 doctors agree

In brief: Not a routine test

The general consensus is that apolipoprotein b levels do not provide more information than LDL levels.
The exception being rare metabolic disorders.

In brief: Not a routine test

The general consensus is that apolipoprotein b levels do not provide more information than LDL levels.
The exception being rare metabolic disorders.
Dr. Gurmukh Singh
Dr. Gurmukh Singh
Thank
Dr. William Cromwell
Clinical Lipidology
1 doctor agrees

In brief: To Assess Therapy

Ldl can be estimated by ldl-c or measured by particle number (apob or NMR ldl-p).
When ldl-c and ldl-p disagree (due to cholesterol variability per particle) cvd risk tracks with LDL particle number. In addition to ldl-c and non-hdl-c (total cholesterol minus hdl-c) goals, expert panel recommendations advise if apob or ldl-p is elevated treatment should be changed to reach an apob or ldl-p target.

In brief: To Assess Therapy

Ldl can be estimated by ldl-c or measured by particle number (apob or NMR ldl-p).
When ldl-c and ldl-p disagree (due to cholesterol variability per particle) cvd risk tracks with LDL particle number. In addition to ldl-c and non-hdl-c (total cholesterol minus hdl-c) goals, expert panel recommendations advise if apob or ldl-p is elevated treatment should be changed to reach an apob or ldl-p target.
Dr. William Cromwell
Dr. William Cromwell
Thank
Dr. James Underberg
Internal Medicine

In brief: Metabolic syndrome

Patients with obesity, Insulin resistance , pre- diabetes and metabolic syndrome often have normal LDL cholesterol levels wi low HDL and high tg's these patients have increases apo b due to tg flux into LDL from vldl with the generation of increased numbers of small dense LDL particles and elevated apob levels not predicted by LDL and non-hdl .
Much data: several groups & countries recommend this.

In brief: Metabolic syndrome

Patients with obesity, Insulin resistance , pre- diabetes and metabolic syndrome often have normal LDL cholesterol levels wi low HDL and high tg's these patients have increases apo b due to tg flux into LDL from vldl with the generation of increased numbers of small dense LDL particles and elevated apob levels not predicted by LDL and non-hdl .
Much data: several groups & countries recommend this.
Dr. James Underberg
Dr. James Underberg
Thank
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