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What happens when your p53 genes are overactive?

1 doctor weighed in
Dr. Ed Friedlander
Pathology

In brief: Bad information

Mutated p53 passed from parent to child is underactive and predisposes one to early and unusual cancers.
As a cancer develops, p53 activity is often lost through mutation. There's a mutant mouse with overactive p53 that seems to age rapidly because p53 clears cells that may be injured. Don't worry about it.

In brief: Bad information

Mutated p53 passed from parent to child is underactive and predisposes one to early and unusual cancers.
As a cancer develops, p53 activity is often lost through mutation. There's a mutant mouse with overactive p53 that seems to age rapidly because p53 clears cells that may be injured. Don't worry about it.
Dr. Ed Friedlander
Dr. Ed Friedlander
Thank
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