6 doctors weighed in:
Can I get coronary artery disease after a heart transplant?
6 doctors weighed in

Dr. Marco Paliotta
Surgery - Thoracic
4 doctors agree
In brief: Yes
Yes, you can develop CAD after a heart transplant but the reasons are usually different.
You'll probably be committed to a fairly healthy lifestyle after a heart transplant so the CAD isn't of the typical kind: i.e. Related to high cholesterol, high blood pressure, lifestyle, etc. It develops due to a chronic rejection by your immune system against the transplanted heart.

In brief: Yes
Yes, you can develop CAD after a heart transplant but the reasons are usually different.
You'll probably be committed to a fairly healthy lifestyle after a heart transplant so the CAD isn't of the typical kind: i.e. Related to high cholesterol, high blood pressure, lifestyle, etc. It develops due to a chronic rejection by your immune system against the transplanted heart.
Dr. Marco Paliotta
Dr. Marco Paliotta
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1 comment
Dr. Michael Zevitz
It frequently occurs as a consequence of immunosuppressive medication such as Cyclosporine. Approximately 50% of patients who received heart transplantation develop at least one blocked coronary artery over 70% within 1-5 years after transplant.
In brief: Good Question
Depending on the age and condition of the donor heart, and the age and metabolic state of the recipient, atherosclerosis can develop in the donor heart coronary arteries.
In addition, the chronic rejection process has some similar characteristics to native heart coronary artery disease. Prevention requires good nutrition, exercise, and close monitoring by your transplant team.

In brief: Good Question
Depending on the age and condition of the donor heart, and the age and metabolic state of the recipient, atherosclerosis can develop in the donor heart coronary arteries.
In addition, the chronic rejection process has some similar characteristics to native heart coronary artery disease. Prevention requires good nutrition, exercise, and close monitoring by your transplant team.
Dr. Stuart Flechner
Dr. Stuart Flechner
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