What is the relationship between hypertension and cardiac output?

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4 doctors weighed in:

# What is the relationship between hypertension and cardiac output?

4 doctors weighed in

Dr. Michael Fenster

Internal Medicine - Cardiology

## In brief: Mathematical

The relationship can be expressed as a variant of darcy' law; flow (q) = pressure/resistance.

In the human circulatory system: q = (map – rap)/tpr (map = mean aortic (or arterial) blood pressure in mmhg, RAP = mean right atrial pressure in mmhg and tpr = total peripheral resistance in dynes-sec-cm-5.) however, as map>>rap, , this can be simplified to: q~map/tpr. Map is obviously affected by htn.

## In brief: Mathematical

The relationship can be expressed as a variant of darcy' law; flow (q) = pressure/resistance.

In the human circulatory system: q = (map – rap)/tpr (map = mean aortic (or arterial) blood pressure in mmhg, RAP = mean right atrial pressure in mmhg and tpr = total peripheral resistance in dynes-sec-cm-5.) however, as map>>rap, , this can be simplified to: q~map/tpr. Map is obviously affected by htn.

Dr. Michael Fenster

Thank

1 comment

Dr. Gopinath Upamaka

Haha. He asked!

Dr. Bennett Werner

Internal Medicine - Cardiology

## In brief: Complicated

The equation is: co equals bp/total peripheral resistance.

If tpr is constant, co rises when BP rises but since that isn't the case, there is a complicated relationship between co and BP which tends to be unpredictable. Tpr is the resistance of the blood vessels and depends on blood viscosity, radius of the vessels to the 4th power, and length and # of vessels & depends on arteriolar tone.

## In brief: Complicated

The equation is: co equals bp/total peripheral resistance.

If tpr is constant, co rises when BP rises but since that isn't the case, there is a complicated relationship between co and BP which tends to be unpredictable. Tpr is the resistance of the blood vessels and depends on blood viscosity, radius of the vessels to the 4th power, and length and # of vessels & depends on arteriolar tone.

Dr. Bennett Werner

Thank

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