11 doctors weighed in:
What is an alternative to iodine used in CT with contrast? Say, someone is allergic to shellfish....What is an alternative contrast to use?
11 doctors weighed in

Dr. Paul Carter
Internal Medicine - Allergy & Immunology
5 doctors agree
In brief: Reaction to contrast
Contrast media reactions are often described as allergy but in truth are not allergy.
The high concentration of the contrast can shock cells called basophils into releasing their granules filled with histamine. This causes the same reaction as the histamine release due to allergy. Shellfish allergy has nothing to do with iodine or contrast. Low osmolality contrast & premedication helps.

In brief: Reaction to contrast
Contrast media reactions are often described as allergy but in truth are not allergy.
The high concentration of the contrast can shock cells called basophils into releasing their granules filled with histamine. This causes the same reaction as the histamine release due to allergy. Shellfish allergy has nothing to do with iodine or contrast. Low osmolality contrast & premedication helps.
Dr. Paul Carter
Dr. Paul Carter
Thank
1 comment
Dr. Steven Machtinger
A really excellent answer. Thank you Dr. Carter.
Dr. Michael Korona
Radiology - Interventional
2 doctors agree
In brief: Get
Premedicated if your worried and have the test.
Shell fish allergy doesn't really increase your risk of allergy to contrast in my opinion. I have a shell fish allergy so i understand your concern. If my patients are worried, i premedicate them.

In brief: Get
Premedicated if your worried and have the test.
Shell fish allergy doesn't really increase your risk of allergy to contrast in my opinion. I have a shell fish allergy so i understand your concern. If my patients are worried, i premedicate them.
Dr. Michael Korona
Dr. Michael Korona
Thank
Dr. Andrew Murphy
Internal Medicine - Allergy & Immunology
In brief: Not related
Shellfish allergy and contrast reactions are not related.
The major shellfish allergen is tropomyosin. The issue with contrast reactions is related to the concentration of the dye used.

In brief: Not related
Shellfish allergy and contrast reactions are not related.
The major shellfish allergen is tropomyosin. The issue with contrast reactions is related to the concentration of the dye used.
Dr. Andrew Murphy
Dr. Andrew Murphy
Thank
Dr. Howard Lelvowitz
Internal Medicine
In brief: See below
Mri is one alternative or Benadryl (diphenhydramine) and Prednisone prioir to the procedure if absolutely necessary.

In brief: See below
Mri is one alternative or Benadryl (diphenhydramine) and Prednisone prioir to the procedure if absolutely necessary.
Dr. Howard Lelvowitz
Dr. Howard Lelvowitz
Thank
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