What are annonaceous acetogenins?

Pawpaw tree extracts. These are derivatives of long-chain fatty acids which are potent inhibitors of mitochondrial & cytoplasmic production of atp & related nucleotides. Their cytotoxicity shows great promise as antitumor, pesticidal, antimalarial, anthelmintic, antiviral, and antimicrobial agents. Products for treating head lice, fleas, & ticks have been developed. Research progresses.