4 doctors weighed in:

How could Down syndrome be missed on targeted ultrasound in a 40 year old?

4 doctors weighed in
Dr. James Ferguson
Pediatrics
1 doctor agrees

In brief: Screening vs confirm

By definition a screening test is done to more individuals to select the group at higher risk for a problem that justifies a greater cost definitive test.
All screening tests can be falsely negative or positive. The definitive tests for DS require chromosome analysis. This can be done in limited centers by finding fetal cells in mothers blood, or by CVS or amniocentesis.

In brief: Screening vs confirm

By definition a screening test is done to more individuals to select the group at higher risk for a problem that justifies a greater cost definitive test.
All screening tests can be falsely negative or positive. The definitive tests for DS require chromosome analysis. This can be done in limited centers by finding fetal cells in mothers blood, or by CVS or amniocentesis.
Dr. James Ferguson
Dr. James Ferguson
Thank
Dr. Casey Younkin
Obstetrics & Gynecology
1 doctor agrees

In brief: It can be.

There are markers for down's on ultrasound, but they are variable and in about 40% of cases they aren't specific enough to be sure, and so there are other tests (such as papp-a, AFP ) to help increase sensitivity.

In brief: It can be.

There are markers for down's on ultrasound, but they are variable and in about 40% of cases they aren't specific enough to be sure, and so there are other tests (such as papp-a, AFP ) to help increase sensitivity.
Dr. Casey Younkin
Dr. Casey Younkin
Thank
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