What is hereditary non-polyposis colorectal cancer (hnpcc) vs familial adenomatous polyposis (fap)?

Both inherited. In fap presents as colonic polyps ( gardners syn will have other tumors ) , autosomal recessive due to mutations in gate keeper, tumor suppres gene. On the contrary hnpcc or lynch syndrome. Is autosomal dominant, due to dna mismatch in repair, associated with other cancers of stomach, endomet. Ca, ovary, brain, skin etc.

Related Questions

Familial adenomatous polyposis--how often does it progress to cancer?

Nearly always. Adenomatous polyposis coli (apc) nearly always leads to colon cancer. Prophylactic colectomy is recommended for any one with multiple polyps due to apc. Read more...
Polyposis. The risk of colon cancer is eight times higher in patients with familial polyposis than the general population. Read more...

Is it still possible for me to have familial adenomatous polyposis if parent had colon cancer?

Yes if parent has it. Yes if parent had colon cancer due to familial adenomatous polyposis, you could have inherited, only way to rule out is to see your physician , and have a colonascopy done. Read more...
If parent had APC. A parent having colon cancer is not how one gets adenomatous polyposis coli (apc). If one of your parents had apc only then you would be at risk for apc. You are still at risk for colon cancer and should follow your doctor's advice for colon cancer screening. Read more...

How is familial adenomatous polyposis inherited?

Autosomal dominant. Enter omim in your browser and go to the database of all inherited diseases. Autosomal dominant means that affected individuals have one normal and one abnormal gene copy, the abnormal one dominating to cause disease. An affected person has a 50% chance to pass on the abnormal gene and fap with each pregnancy. Read more...

How is familial adenomatous polyposis inherited?

Autosomal Dominant. Fap is inherited in an autosomal dominant fashion. This means that if one parent has the gene, and the other parent doesn't, each child has a 50% chance of receiving the gene for fap. The disease causes hundreds of polyps to form in the colon (see the picture), leading to colon cancer. Read more...

Who should undergo genetic counseling for hereditary non-polyposis colorectal cancer (hnpcc)?

Family history. There are a number of different inherited defects that cause hnpcc. A person with strong family history of colon cancer, occurring at a young age should seek counseling. Read more...

Has anyone heard of fap (familial adenomatous polyposis) outside the amish community?

Yes sure. Fap occurs in approximately 1/10, 000 to 1/30, 000 live births, and accounts for less than 1 % of the total colon cancer risk in the United States it happens not only in amish community- but also in other population- such as in ashkenazi jewish population for instance, etc. Read more...

I'm having constipation, could it be familial adenomatous polyposis and what are the other symptoms?

Constipation can . Occur without the familial adenomatosis. If you feel you are at risk for fap, you need to see a GI or colon and rectal surgeon and get a colonoscopy. Only then can your constipation be addressed properly. Read more...
Familial polyposis . Patients are usually asymptomatic but can present with diarrhoea, rectal bleeding abdominal pain , mucous discharge through anus . Constipation can occur but usually at stage where obstruction has occurred . http://patient.info/doctor/bowel-colonic-polyps-pro. Read more...

Is it bad to have familial adenomatous polyposis at the age of 49?

R/O colon cancer etc. Fap is an autosomal dominant --presented with 100's adenomatous colorectal polyps. In the classic fap- the risk for colorectal cancer is 100% by the time you reach 45Y.O. In adidition, there is also increased risk for duodenal, stomach, thyroid, CNS cancer.Colectomy is recommended to reduce your risk. Upper endoscopy is also recommended. You should see a surgeon re-colectomy-and genetic counsellor. Read more...

What is the definition or description of: familial adenomatous polyposis?

Hereditary condition. Hereditary condition characterized by multiple polyps in colon which are neoplastic and have the potential for malignancy. Read more...