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What is a fish test on amniotic fluid?

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Dr. Nikolaos Zacharias
Obstetrics & Gynecology - Maternal Fetal Medicine

In brief: Rapid look for Down.

Fish stands of fluorescent in-situ hybidization of the chromosomes in fetal cells obtained after invasive prenatal diagnosis (such as amniocentesis).
When time is of the essence, fish can give a preliminary result of fetal aneuploidy (e.g. Down syndrome) within 24 hours from the procedure. It should be followed by a full karyotype and chromosomal microarray analysis.

In brief: Rapid look for Down.

Fish stands of fluorescent in-situ hybidization of the chromosomes in fetal cells obtained after invasive prenatal diagnosis (such as amniocentesis).
When time is of the essence, fish can give a preliminary result of fetal aneuploidy (e.g. Down syndrome) within 24 hours from the procedure. It should be followed by a full karyotype and chromosomal microarray analysis.
Dr. Nikolaos Zacharias
Dr. Nikolaos Zacharias
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