What are p53 genes?

Tumor supression. The p53 gene, is a tumor suppressor gene, i.e., its activity stops the formation of tumors. If a person inherits only one functional copy of the p53 gene from their parents, they are predisposed to cancer and usually develop several independent tumors in a variety of tissues in early adulthood. This condition is rare, and is known as li-fraumeni syndrome.

Related Questions

What happens when your p53 genes are overactive?

Bad information. Mutated p53 passed from parent to child is underactive and predisposes one to early and unusual cancers. As a cancer develops, p53 activity is often lost through mutation. There's a mutant mouse with overactive p53 that seems to age rapidly because p53 clears cells that may be injured. Don't worry about it. Read more...

What is a defective P53 gene. Is it inheritable?

Cell regulation. The P53 gene is thought to be involved in regulating cell death. When the P53 gene mutates or has a change from the normal gene, this may lead to types of cancers. Read more...