7 doctors weighed in:
What is interstitial cystitis caused by?
7 doctors weighed in

Dr. Mitchell Schuster
Obstetrics & Gynecology - Urogynecology
4 doctors agree
In brief: Breakdown in GAG
There is a breakdown in the gag layer of the bladder.
Gag stands for glucoseaminoglycan and it is a microscopic layer that is supposed to help with protection of the mucous layer of the bladder. There is a lot of research going into this area and there is a significant connection between interstitial cystitis and endometriosis. Right now we are managing the symptoms as best we can. No cure yet!

In brief: Breakdown in GAG
There is a breakdown in the gag layer of the bladder.
Gag stands for glucoseaminoglycan and it is a microscopic layer that is supposed to help with protection of the mucous layer of the bladder. There is a lot of research going into this area and there is a significant connection between interstitial cystitis and endometriosis. Right now we are managing the symptoms as best we can. No cure yet!
Dr. Mitchell Schuster
Dr. Mitchell Schuster
Thank
1 comment
Dr. Stephen Rodrigues
This is a new look at an old idea. Janet G. Travell, MD a pain pioneer concluded that chronic tissue pain was caused by numerous trigger points in muscle fibers causing the muscles to contract compressing nerves, vessels and alter the flow of lymphatics. The pyramidalis and pelvic floor muscles are the cause. So this is a mechanical cause and requires a manual treatment. Massage and Acupuncture! See files.
Dr. Robert Harris
Obstetrics & Gynecology - Urogynecology
1 doctor agrees
In brief: Unknown
Although IC seems to be more common in women with other ayto0immue processes, there is no known "cause" for IC.
Interstital Cystitis is more of a compilation of symptoms rather that a true "condition". Therefore, treating the symptoms, e.g. urinary frequency and urgency, pain in the bladder area, painful intercourse, pelvic pain, etc., is the best approach to improving outcomes.

In brief: Unknown
Although IC seems to be more common in women with other ayto0immue processes, there is no known "cause" for IC.
Interstital Cystitis is more of a compilation of symptoms rather that a true "condition". Therefore, treating the symptoms, e.g. urinary frequency and urgency, pain in the bladder area, painful intercourse, pelvic pain, etc., is the best approach to improving outcomes.
Dr. Robert Harris
Dr. Robert Harris
Thank
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