3 doctors weighed in:

What cause the impairment of neurons in Parkinson's disease?

3 doctors weighed in
Dr. Djamchid Lotfi
Neurology
1 doctor agrees

In brief: Unknown

In the etiology of this disease toxic substances (like heavy metals, specific chemicals) infectious e.
g. Viral) genetic and environmental factors have been implicated but no definite theory exists.

In brief: Unknown

In the etiology of this disease toxic substances (like heavy metals, specific chemicals) infectious e.
g. Viral) genetic and environmental factors have been implicated but no definite theory exists.
Dr. Djamchid Lotfi
Dr. Djamchid Lotfi
Thank

In brief: Lewy Bodies

Polymers of a-synuclein protein form into "clumps" (intraneuronal inclusions) due to faulty "trash removal" processes in the neurons.
As a result, cellular activity is disrupted. Other problems, such as oxidative stress causing mitochondria damage (energy producing portion of cell) lead to programmed cell death, or "apoptosis." many other facets of this cascade of problems are yet to be understood.

In brief: Lewy Bodies

Polymers of a-synuclein protein form into "clumps" (intraneuronal inclusions) due to faulty "trash removal" processes in the neurons.
As a result, cellular activity is disrupted. Other problems, such as oxidative stress causing mitochondria damage (energy producing portion of cell) lead to programmed cell death, or "apoptosis." many other facets of this cascade of problems are yet to be understood.
Dr. Robert Hutchman
Dr. Robert Hutchman
Thank
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