What cause the impairment of neurons in Parkinson's disease?

Unknown. In the etiology of this disease toxic substances (like heavy metals, specific chemicals) infectious e.g. Viral) genetic and environmental factors have been implicated but no definite theory exists.
Lewy Bodies. Polymers of a-synuclein protein form into "clumps" (intraneuronal inclusions) due to faulty "trash removal" processes in the neurons. As a result, cellular activity is disrupted. Other problems, such as oxidative stress causing mitochondria damage (energy producing portion of cell) lead to programmed cell death, or "apoptosis." many other facets of this cascade of problems are yet to be understood.

Related Questions

What are the causes and simple remedies for parkinson disease (including vastu remedies)?

Exercise & medicine. Parkinson disease is caused by a loss of dopamine-producing cells in the brain. When one loses enough of these, the symptoms begin. The treatment includes cardiovascular exercise, but mostly by medication that replicates the effect of the dopamine. There is no evidence for any benefit of vastu remedies. Read more...
Parkinson's disease. Parkinsons disease (pd) is a degenerative disorder of the central nervous system with motor symptoms due to the death of dopamine-generating cells in the substantia nigra. Later in its course cognitive and behavioral problems may occur in addition. School medicine teaches that there is no cure for pd, but medications, surgery and multidisciplinary management can provide symptomatic relief. Read more...

Can you tell me the causes and simple remedies for parkinson disease (including vastu remedies)?

Vastu remedies. There is no known cause for parkinson's disease. There are several excellent western medical options for parkinson's disease. A neurologist can help with a treatment plan. Light a candle in the southeast portion of the house on a daily basis for good health. Please see a vastu guru for further vastu remedies in regard to parkinson's disease. Read more...

What would be the most common causes and simple remedies for parkinson disease (including vastu remedies)?

Exercise & medicine. Parkinson disease is caused by a loss of dopamine-producing cells in the brain. When one loses enough of these, the symptoms begin. The treatment includes cardiovascular exercise, but mostly by medication that replicates the effect of the dopamine. There is no evidence for any benefit of vastu remedies. Read more...

I may have some symptoms of parkinson disease; is it possible that some medication cause symptoms like these?

Possibly. There are a number of medications with side-effects that mimc parkinson disease. Reglan and Compazine are very common examples. Similarly, a number of anti-psychotic and mood stabilizing medications can do so, as well...E.G. Haldol, risperdal, abilify (aripiprazole)...There are very many...Even Depakote can, through a different mechanism...And, less commonly, ssri's, such a Paxil and Prozac (and others)... Read more...

I had parkinson disease for 12 years now. With my daily medication no one will know I have this ailment. Wouldn't my age 62 cause it to be worse?

Not necessarily. Congratulations on having a medication regimen that keeps the disease in check. Parkinson diseae affects different people differently; be happy you have control right now! Read more...

How could parkinson disease be prevented?

Parkinson. Despite a good deal of investigation so far there is no known causes of Parkinson's except for those drug induced. So until the source is found the concept of prevention remains remote. Read more...