8 doctors weighed in:

Why are thymectomies not done on patients with multiple sclerosis like with myasthenia gravis?

8 doctors weighed in
5 doctors agree

In brief: See answer below

Myasthenia gravis is an autoimmune disorder, driven by imbalances of immune cell subtypes that is distinctly different from that in ms.
Removing the thymus in myasthenia gravis can reduce the number of immune cells in that disorder, and help reduce disease activity. The same would not be expected for ms.

In brief: See answer below

Myasthenia gravis is an autoimmune disorder, driven by imbalances of immune cell subtypes that is distinctly different from that in ms.
Removing the thymus in myasthenia gravis can reduce the number of immune cells in that disorder, and help reduce disease activity. The same would not be expected for ms.
Dr. Virginia Simnad
Dr. Virginia Simnad
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Dr. Olav Jaren
Neurology
1 doctor agrees

In brief: Cause of autoimmune

Thymectomy has been shown to be a helpful treatment for some people with myasthenia gravis, but no other autoimmune diseases.
This includes multiple sclerosis. In this case, the cause of the disease is not known to be linked to the action of B lymphocytes, which are modulated by cells that are produced by the thymus. Myasthenia is also linked to thymus hyperplasia and thymoma, MS is not.

In brief: Cause of autoimmune

Thymectomy has been shown to be a helpful treatment for some people with myasthenia gravis, but no other autoimmune diseases.
This includes multiple sclerosis. In this case, the cause of the disease is not known to be linked to the action of B lymphocytes, which are modulated by cells that are produced by the thymus. Myasthenia is also linked to thymus hyperplasia and thymoma, MS is not.
Dr. Olav Jaren
Dr. Olav Jaren
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In brief: Different diseases

Myasthenia gravis affects neuromuscular junction in the periphery and MS affects nerve coverings in the central nervous system.
The immune process is completely different and distinct in each disorder.

In brief: Different diseases

Myasthenia gravis affects neuromuscular junction in the periphery and MS affects nerve coverings in the central nervous system.
The immune process is completely different and distinct in each disorder.
Dr. Bennett Machanic
Dr. Bennett Machanic
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Dr. Bennett Machanic
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