Lsd conspiracy. Most of the studies from 1960 to 1980 were culture tainted with the issue of conspiracy. In 2004 study by nicols and other revealed that potent hallucinogenic drug lysergic acid diethylamide (lsd) dynamically influences the expression of a small collection of genes within the mammalian prefrontal cortex. They identified and characterized expression patterns of a new collection of three genes.
It doesn't, but... There were some junk-science petri dish studies in the 1960s but nobody's shown genetic damage from the stuff, either as a cause of cancer or as a source of new mutations that can be passed to the kids. Even tobacco doesn't do the latter. These were intensely political, with the public seeing LSD-takers as a huge menace and demanding scare stuff. It's bad for you; please don't do it.