Depends. Aspirin offers benefits and dangerous side effects. For a thorough discussion of the topic see http://mdprevent.Blogspot.Com/2013/02/dr-oz-and-asprin-is-he-being.Html. Aspirin isn't for everyone and high cholesterol alone may not be an indication to take it. Other factors such as family history of heart attacks and strokes, high blood pressure, obesity, etc. Must weigh in so speak with your doctor.