Anything wrong with the zyrtec (cetirizine) allergy medicine in pregnancy?

Usually no. Zyrtec (cetirizine) is rated by the food and drug admistration as category b in pregnancy. Animal reproductive studies have not demonstrated a risk. There have not been well controlled human studies in pregnancy to prove safety in humans (very few medications have been proven safe in controlled studies in pregnancy as few such studies are ever done). Avoid zyrtec (cetirizine) d in the first trimester.