2 doctors weighed in:

Explain vascular endothelial growth factor?

2 doctors weighed in
Dr. Andrew Turrisi
Radiation Oncology

In brief: Metastases are

A mystery, but there are clear events necessary.
Establishing a blood supply that delivers nutrients and carts away metabolites seem necessary (some tumors grow nicely in anaerobis, acidic, toxic environs). The colony secretes a local paracrine stimulus to develop a blood supply. Vegf also seems critical in development embronically of the cardiovascular system.

In brief: Metastases are

A mystery, but there are clear events necessary.
Establishing a blood supply that delivers nutrients and carts away metabolites seem necessary (some tumors grow nicely in anaerobis, acidic, toxic environs). The colony secretes a local paracrine stimulus to develop a blood supply. Vegf also seems critical in development embronically of the cardiovascular system.
Dr. Andrew Turrisi
Dr. Andrew Turrisi
Thank
Dr. Ed Friedlander
Pathology

In brief: Guide-molecule

Wherever new tissue is growing, vegf guides the new blood vessels.
We have medicines that suppress vegf and slow cancers; they help in some cases. Good luck.

In brief: Guide-molecule

Wherever new tissue is growing, vegf guides the new blood vessels.
We have medicines that suppress vegf and slow cancers; they help in some cases. Good luck.
Dr. Ed Friedlander
Dr. Ed Friedlander
Thank
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