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The difference between tylenol (acetaminophen) with codeine #3 and #4?

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Dr. Alvin Lin
Internal Medicine - Geriatrics

In brief: Amount of Codeine

Both t#3 & t#4 contain 300mg Acetaminophen (tylenol).
But while t#3 also contains 30mg of codeine, t#4 contains 60mg or twice as much. Fyi maximum daily dose of Codeine for pain purposes is 360mg; for Acetaminophen the maximum dose has been lowered from 4, 000mg daily down to 3, 000mg daily assuming you have no liver issues and don't drink alcohol to excess.

In brief: Amount of Codeine

Both t#3 & t#4 contain 300mg Acetaminophen (tylenol).
But while t#3 also contains 30mg of codeine, t#4 contains 60mg or twice as much. Fyi maximum daily dose of Codeine for pain purposes is 360mg; for Acetaminophen the maximum dose has been lowered from 4, 000mg daily down to 3, 000mg daily assuming you have no liver issues and don't drink alcohol to excess.
Dr. Alvin Lin
Dr. Alvin Lin
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