Is Wellbutrin (100mg 2x/day), Fluoxetine (30mg) and Abilify (aripiprazole) (1mg, 2mg after a week) a safe combination for anxiety and depression?

Probably. Depending on yourneeds the combination seems reasonable. If the fluoxetine alone or in combination with wellbutrin doesn't remove/reduce depression, the addition of Abilify (aripiprazole) often helps. If, after a time this is not helpful... you didn't say you were in psychotherapy, but I would recommend it also.