Colon cancer patient. Cea rising on irinotecan. It was started in oct when CEA was 8. Dec cea-9, jan CEA 10. Is this treatment failure?

Not necessarily. Chemotherapy can cause the CEA to rise when started. In addition, that is not a significant rise to make me concerned. Also, one wants to see a trend. Meaning, 8, 10, 15, 20 before one thinks failure. In addition, don't treat a number, treat what can be seen on the CT scan. Hope this helps.

Related Questions

A CEA rise upon starting irinotecan in person with colon cancer suggest treatment not working? Cea was Oct 8, dec 9, jan 10.

Very good question! The answer's somewhat debated. 1st, CEA levels even in the presence of cancer r somewhat variable, so my 1st question is *how much* did the values rise? An increase of 1 mcg/L may not b significant, though an increase of 100 mcg/L is definitely so. Also, levels increase if u r around cigarette smoke. Lastly, CEA could be released from cancer cells as they die. TTYD (Oncologist) to interpret numbrs. Read more...

In colon cancer patients, y do some hae higher cea"s (like in the 100, s) and some don't? My dad's CEA stands at 10 at present while on irinotecan

Change in level. Changes in the level of CEA are more useful for monitoring the course of disease than one reading. There is wide variation in CEA levels in patients with colon as well as other cancers. Read more...

Cea is rising as soon as started irinotecan for colon cancer. Primary already removed in march. Then found a liver met and node. Cea now 10.?

Disease progression. This does not necessarily mean that the chemotherapy is not working. You do need to be aware of the long-term outcome. My hope is that the patient will still get several more good years. If this is you, then you have a right to know the likely effects of whatever treatments you are offered. Read more...

What would be best chemo / treatment after irinotecan n Xeloda (capecitabine) failed for colon cancer with mets?

Difficult to answer. recommended chemotherapy regimens change regularly depending on the results of studies. Your oncologist should keep on top of those studies and will be able to recommend the next approved therapy or any experimental trials which may be available. I would talk further with your oncologist before making any plans. Good luck. Read more...