At advanced gastric int. Metaplasia or at dysplasia, is the urea breath test still effective?

Yes. The breath test for helicobacter pylori contains a chemical called urea, which is attached to a carbon atom. The bacteria break down the urea thereby releasing the carbon, which is eventually exhaled in the breath. The presence of the bacteria is highly associated with malignant transformation in the stomach and the presence of dysplasia is a suggestion that cancer is forming and must be treated.

Related Questions

Once someone has progressed to gastric intestinal metaplasia, does a urea breath test still detect H pylori?

Yes. The urea breath test is a rapid method to identify infections by Helicobacter pylori,implicated in gastritis, gastric ulcer, and eventual malignancy based upon the ability of H. pylori to convert urea to ammonia and carbon dioxide. The test measures active H. pylori infection. If antibiotics are depressing the amount of H. pylori present, or the stomach conditions are less acidic than normal, the amount of urease present will be lessened. In many untreated cases of malignancy the H.pylori levels are still relatively high with early malignancy, Read more...