Is there a difference between kras wild and KRAS mutant colon cancer?

Chemoresistance. In metstatic colorectal cancer combinations of chemotherapy utilized. Drug combos such as FOLFOX are employed. With a poor response, immunotherapy is added such as the VEGF receptor antibodies or those targeting epidermal growth factor receptors like Erbitux and Vectibix (panitumumab). If the standard or wild type Kras is present in mets, there is a fairly good response but neg activity in mutated Kras.
Yes definitely. These are two different types of colon cancer and require different treatment approach. It is better to have KRAS wild type than KRAS mutated type, the latter has but limited treatment options, in case the Cancer recurs.
Yes. If your cancer has mutant KRAS, you're pretty much guaranteed of not responding at all to a couple of the pricey new chemotherapy agents. KRAS is usually activated by point mutation, but sometimes by amplification instead (more copies). Good luck with this and I hope your treatment, whatever the genotype, is successful.

Related Questions

Which chemo therapy is most effective for KRAS mutant metastic colon cancer?

Same drugs as other. Same chemotherapy drugs are used for treating both types of colon cancer. The only difference is lack of benefit from EGFR inhibitors(Cetuximab and Panitumumab). Avastin (bevacizumab) also works in both types. I trust that you know there are 3 chemo drugs that are widely used(5FU or Capecitabine, Irinotecan and Oxaliplatin) Read more...

How can you tell the difference between hemmorhoids and colon cancer? Even though the symptoms are very similar, what are the major differences?

Colonoscopy & biopsy. Hemorrhoids are abnormally enlarged veins at the anus that can flare secondary to constipation, diarrhea, straining, dehydration, pregnancy, being overweight, and several other conditions. Colon cancer would be unusual in an 18 year old; most are detected after age 50. Symptoms may not be present in early cases, but can include blood in stool, obstruction, weight loss, or an abdominal mass. Read more...
Exam or colonoscopy. Many people present with "piles" and this can actually be the issue or one of many other problems that your doctor can help there are dietary, behavioral, hygiene modifications as well as procedures that can help with these common problems. Both constipation and diarrhea can lead to this condition as well it is best if you consult with a general or colorectal surgeon to help with this matter. Read more...
Can be difficult. GREAT question although if we are talking about you it would be very unusual for a 19 yo to have colorectal cancer. The point is it really is almost impossible to know for sure and therefore everyone who has rectal bleeding or a change in bowel habits should see a provider even though the most common cause of both of these is not cancer. Read more...

What is the difference between intestinal cancer and colon cancer?

Specific site. Intestinal cancer can mean any type of cancer affecting any portion of the intestines (from the small intestine to the large intestine). Colon cancer affects the large intestine only. Read more...
Most common. Intestinal cancer is colon cancer or adenocarcinoma of the large intestine. Cancer of the small intestine is quite a bit less common and can be of various tissue types. Read more...

What is the difference between a colon cancer and intestinal cancer?

Depends. A colon cancer is a cancer of the large intestine. An intestinal cancer could be located anywhere in the small or large intestine. But small intestinal cancer is quite rare, so i suppose that most "intestinal" cancers would be located in the colon statistically. Read more...
Location, Incidence. Colon cancer arises from a site involving the large intestine commonly called the colon (ascending, transverse, descending, sigmoid). Intestinal cancer usually refers to small intestinal cancer that arises from the duodenum, jejunum or ileum. Colon cancer is much more common compared to cancer arising from the small intestines which is considered rare. Read more...

What is the difference in the various stages of colon cancer?

Survival, but..... Used to be, the short answer was simply survival risk with stage 1 having the best prognosis and stage IV the worst. While stages 1/2 still have the highest survival rates but improved surgical techniques and chemotherapy and i'd add lifestyle changes, have leveled the playing field greatly. Colon cancer, even advanced is often quite treatable. Read more...

Colon cancer or colorectal cancer, what's the difference?

Location. Cancers that arise from the epithelium of the large intestine are similar in most ways whether they are in the colon or rectum. Discussions of "colon cancer" unspecified usually mean "colorectal" unless stated otherwise. Usage, including by me, is often sloppy. Read more...