Can a person develop a mosquito allergy later in life?

Mosquito Menace. Each of us possesses an immune reaction to the anticoagulant saliva of mosquitoes, some more than others. It is possible that a person with a mild, local cellular reaction could later develop a more systemic "anaphylactoid" reaction to a bite, however this is extremely rare. Unlike bee or wasp venom, mosquito saliva is not designed to kill or paralyze but designed to anticoagulate and dilate.