Is the a difference between metoprolol succinate and metoprolol tartrate?

Duration. Metoprolol succinate is an extended-release version dosed once daily, meanwhile, Metoprolol Tartrate is an immediate-release (short duration) version dosed twice daily for long-term management. Both can treat hypertension and angina (chest pain), however, succinate is also indicated for heart failure and tartrate can be used to treat an acute myocardial infarction (heart attack).
Yes. Tartrate is short acting and needs to be taken twice daily. The succinate form is long acting and is taken once a day.