1 doctor weighed in:
Why do doctors tell you not smoke or to use caffine before the methacholine challenge test?
1 doctor weighed in

Dr. Asaf Presente
Internal Medicine - Pulmonary Critical Care
In brief: For unaltered result
Since both caffeine (which can relax the bronchial muscle tone) and smoking - (which can irritate bronchial muscle tone making it more sensitive) - can affect the test - these factors and others are to be avoided ahead of a methacholine test which is trying to guage the patient's baseline bronchial reactivity (often to investigate the presence of asthma).

In brief: For unaltered result
Since both caffeine (which can relax the bronchial muscle tone) and smoking - (which can irritate bronchial muscle tone making it more sensitive) - can affect the test - these factors and others are to be avoided ahead of a methacholine test which is trying to guage the patient's baseline bronchial reactivity (often to investigate the presence of asthma).
Dr. Asaf Presente
Dr. Asaf Presente
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