3 doctors weighed in:

What are the risks doing the methacholine challenge?

3 doctors weighed in
Dr. Fernando Garcia
Anesthesiology
1 doctor agrees

In brief: Asthma diagnosing

This test is indicated when the diagnosis of asthma is in question (eg, symptoms are atypical, baseline testing is normal).
There are contraindications to test such as pregnancy, recent heart attack and severe asthma. Also there are medicines, such as bronchodilators and steroids that must be stopped before the test is done to make it valid. Risks include severe asthmatic attack or heart attack.

In brief: Asthma diagnosing

This test is indicated when the diagnosis of asthma is in question (eg, symptoms are atypical, baseline testing is normal).
There are contraindications to test such as pregnancy, recent heart attack and severe asthma. Also there are medicines, such as bronchodilators and steroids that must be stopped before the test is done to make it valid. Risks include severe asthmatic attack or heart attack.
Dr. Fernando Garcia
Dr. Fernando Garcia
Thank
Dr. Steven Cohen
Internal Medicine - Allergy

In brief: Asthma

Methacholine test is used to document changes of obstruction, which can be reversed, compatible with asthma.
Since the test is done in stages, with spirometry between each stage, one should not develop severe symptoms. Patients should not have significant obstruction before starting the test and most pulmonary function labs will not proceed if baseline studies are very abnormal.

In brief: Asthma

Methacholine test is used to document changes of obstruction, which can be reversed, compatible with asthma.
Since the test is done in stages, with spirometry between each stage, one should not develop severe symptoms. Patients should not have significant obstruction before starting the test and most pulmonary function labs will not proceed if baseline studies are very abnormal.
Dr. Steven Cohen
Dr. Steven Cohen
Thank
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