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Which one of these can cause a low MCH and mchc in blood test,when deficient - iron OR b12?

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Dr. Ed Friedlander
Pathology

In brief: Homework?

Iron deficiency produces small cells with less hemoglobin (low MCH, MCHC).
In B12 deficiency, there is no problem making hemoglobin, but making enough DNA is impossible, and the nuclear maturation cannot keep up with hemoglobinization, hence large cells.

In brief: Homework?

Iron deficiency produces small cells with less hemoglobin (low MCH, MCHC).
In B12 deficiency, there is no problem making hemoglobin, but making enough DNA is impossible, and the nuclear maturation cannot keep up with hemoglobinization, hence large cells.
Dr. Ed Friedlander
Dr. Ed Friedlander
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