Can u have atypical cystic fibrosis if u have asthma, severe pancreas involvement & CFTR m470v? Report indicates a 2nd gene may be rare or unknown

Maybe. Surprisingly, M470V is a common variation. Studies have shown 50% of the population has this mutation and actually less likely to cause CF. Most individuals with CF and carry M470V have some other hidden etiology that is the cause, rather than M470V. Genetic expression may be variable and so will be the clinical manifestations. Speak with your doc and a geneticist for specific information.