Which is the better adriamycin (doxorubicin) or ifosfamide for synovial sarcoma?

Usually combined. These 2 chemotherapy drugs are usually combined in treatment of synovial sarcoma. I am not sure that one is better than the other. A study in the 1990s showed that the combination was better than doxorubicin alone.

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Which is the better cytotoxic drug (adriamycin (doxorubicin) or ifosfamide) for synovial sarcoma?

Equally effective. Synovial sarcomas when first seen i.e. in the lower leg/foot area must be resected to obtain cure. If seen late and mets have occurred, in selected areas such as a solitary lung or liver lesion, then resection employed. If multiple mets present then Adriamycin (doxorubicin) and or ifosfamide in combination with carboplat and other drugs may be needed. Chemosensitization studies of fresh tumor bx can help. Read more...