Why do we give anti-estrogen drugs to post-menopausal women with breast cancer?

Anti-estrogen drugs. Anti-estrogen drugs are given to both premenopausal and postmenopausal women whose cancer is estrogen receptor-positive or progesterone receptor-positive. These cancer may grow when exposed to estrogen. Anti-estrogen medications block or reduce estrogen that is normally produced by the ovaries in premenopausal women or by fat cells, liver, adrenal glands or other organs in postmenopausal women.

Related Questions

How do breast cancer anti estrogen pills work?

Starve tumor. Many tumors are fed by estrogen - the main female horomone. Anti-estrogen pills block the effects of estrogen (in a variety of different ways) and thereby starve the tumor from a vital growth factor. Even if you are postmenopausal (or even male) your body still produces estrogen in places like the adrenals and subcutaneous fat. Read more...
Aromatase inhibitor. An aromatase inhibitor blocks the conversion of testosterone like hormones in fat cells to the strong estrogen (estrone). Read more...

If I had breast cancer, can I take estrogen in menopause?

Probably not. You should speak with your oncologist, however, Estrogens are usually not recommended if you have had breast cancer. Read more...
Yes and No. If your breast cancer responded to estrogen, you have a higher risk of problems. You should talk to your oncologist about the risks of taking estrogen. Read more...

What is the difference between anti-estrogens and anti-aromatases for breast cancer?

"cousin-drugs" Tamoxifen ("anti-estrogen") and aromatase inhibitors (ai) are both used for treating breast cancers that are estrogen-receptor +. Ai's are only suitable after menopause but may be slightly more effective; furthermore, they are not associated with any increased risk of uterine cancer like tamoxifen. Read more...
Pharmacology. Anti-estrogens block the receptors to which estrogen attaches on the cell. Anti-aromatases prevent estrogen from being made in the body. Read more...

Can POCS causes both high androgen and estrogen levels if not overweight? Can eating pyhytoestrogens increase breast cancer in women with POCS?

PCOS. PCOS can increase androgens in patients regardless of their weight. The effects on Estrogen are less clear as these levels fluctuate and typically would not be tested in PCOS. The LH and FSH levels are checked but not Estrogen. The effects of Phytoestrogens such as soy on the risk of breast cancer are debatable. There is not specific recommendation for PCOS patients to avoid them. Read more...

If my breast cancer feed off estrogen bein a female how can I reduce it in my body?

"anti-estrogens" Great question. Breast cancer is associated with prolonged high estrogen levels (early menarche, late menopause, children later in life, estrogen replacement rx), not caused, meaning it's not a simple relationship. If you are trying to prevent breast cancer, a low-fat diet is advisable, which may keep estrogen levels down. For ca rx, anti-estrogens such as tamoxifen may counteract the estrogen. Read more...
Iodine. Iodine blocks estrogen receptors - take orally 13.8 mg per day available as iodozyme with biotics need 2pills comes as 6.25mg. Read more...
Anti-hormone drugs. If you have been diagnosed with hormone-receptor positive breast cancer, you should be on a medication to either block estrogen (tamoxifen) or, if you are post-menopausal, to decrease the level of estrogen in your body (letrozole, anastrazole, or exemestane). You can lose weight if you are obese, which will also decrease the estrogen in your body. However, anti-estrogen drugs are very important! Read more...
Avoid estrogens. I agree with the other docs: you should be taking anti-estrogens. But it also helps to avoid xenoestrogens, which come in many forms. Phytoestrogens are in soy and other plant foods; hormone-treated dairy products contain estrogens, and "female" supplements like evening primrose oil are potent sources. Bpas from plastics mimic estrogen in the body; get a metal water bottle! Read more...

Should a 65-year old woman with a family history of breast cancer continue estrogen?

Probably not. This can increase the risk for some breast cancers and endometrial cancer. Having a family history does not help. However, low dose hormone replacement therapy may be possible. It would be wise to see your doctor to be sure. Read more...
Estrogen & breast CA. Oh such a tough decision!if you have two first degree relatives with breast cancer(sister, mother) you should probably consider stopping.However, if you have osteoporsis or significant heart disease in youself or family this has to be considered. Which is greater risk ca or heart/bones?Than factor in how bad you feel when you don't take estrogen...See what i mean? Read more...

What is the reason we give antiestrogen drugs to post-menopausal women who have breast cancer?

Astute question!! Post menopausal women and women who had their ovaries removed still produce sex steroids in the adrenal glands that are later converted to estrogen. Cancer cells learn how to function with those minute quantities of Estrogens and for that reason we target the estrogen receptor pathway in these women. Thank you for that good question. Read more...

What can I do for hot flashes can't take estrogen due to breast cancer in family I lost my mom to cancer?

SSRI;s. Selective Serotonin Reuptake Inhibitors (SSRI's) commonly known as a class of anti-depressants can be effective in minimizing hot flashes. Talk to your GYN MD about this and any other alternatives to estrogen Rx's that may be available. Read more...