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Why do IgE levels increase in patients with atopic dermatitis?

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Dr. Jonathan Field
Pediatrics - Allergy & Asthma

In brief: IgE in atopic dermatitis

Atopic dermatitis seems to involve both B cell production of IgE as well as T cell function in later phases.
The antigens that affect the skin seem to make non-specific IgE production increase. We have recently recognize that staph aureus may be a trigger of the high IgE as there is IGE related to staph. This may drive the eczema even with minimal skin staph carriage rather than true impetigo

In brief: IgE in atopic dermatitis

Atopic dermatitis seems to involve both B cell production of IgE as well as T cell function in later phases.
The antigens that affect the skin seem to make non-specific IgE production increase. We have recently recognize that staph aureus may be a trigger of the high IgE as there is IGE related to staph. This may drive the eczema even with minimal skin staph carriage rather than true impetigo
Dr. Jonathan Field
Dr. Jonathan Field
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