I am starting to use efudex (fluorouracil) precancer cream. Is my whole face going to be a mess?

Efudex (fluorouracil) Skin irritation, burning, redness, dryness, pain, swelling, tenderness, or changes in skin color may occur at the site of application. Eye irritation (e.g., stinging, watering), trouble sleeping, irritability, temporary hair loss, or abnormal taste in the mouth may also occur. Consult your doctor with any of these side effects.