Hair loss. Two types of androgens are involved in the mechanism of male pattern hair loss. These are testosterone and dihydrotestosterone (dht). Dihydrotestosterone is a derivative of testosterone. The enzyme called 5-alpha reductase converts the relatively inactive testosterone to a more potent form, dihydrotestosterone. Thus, the key enzyme involved in androgenetic hair loss is 5-alpha reductase.
Yes! Excess testosterone can cause hirsutism or male pattern facial/body hair in women. Spironolactone acts as anti-androgen to minimize hirsutism. Excess dihydrotestosterone can cause male pattern baldness. Finasteride & Dutasteride are used to stop conversion of t into dht, thereby shrinking prostate & minimize hair loss.
Via conversion 2 DHT. Testosterone is converted into dihydrotestosterone (dht) via 5 Alpha reductase enzyme. Dht is considered poisonous to hair follicles. It is also responsible for prostate enlargement. That's why Finasteride & dutasteride, 5 Alpha reductase inhibitors, are used to lower Dht and thus shrink prostate & allow for hair regrowth. But don't forget that genetics (ethnicity) affects total body & scalp hai.
During puberty what are the functions of testosterone vs dihydrotestosterone? Which has greater influence on sexual development, facial hair & voice?
DHT. Dht has all the masculizing effects from hormones you asked about. Testosterone on its own is anabolic and good to build muscle and wellness effects on your psyche. Dht has all the bad effects. Testosterone converts into dht.