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My dermatologist prescribed clindamycin gel and tretinoin gel (two separate tubes) but didn't give application instructions. Which goes on first?
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Dr. Jennifer Haley
Dermatology
In brief: My recs
Clinda gel should be twice a day and at night use a pea sized amount of the retinoid first then the clinda.
Less is more with a retinoid. More is more irritating, not more effective. You also must be using a benzoyl peroxide wash or the bacteria will become resistant to the clinda. So, wash twice daily with bpo, clinda 2x/day, and retinoid nightly as 1st step. Cerave pm moist last at night.

In brief: My recs
Clinda gel should be twice a day and at night use a pea sized amount of the retinoid first then the clinda.
Less is more with a retinoid. More is more irritating, not more effective. You also must be using a benzoyl peroxide wash or the bacteria will become resistant to the clinda. So, wash twice daily with bpo, clinda 2x/day, and retinoid nightly as 1st step. Cerave pm moist last at night.
Dr. Jennifer Haley
Dr. Jennifer Haley
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