12 doctors weighed in:
Will stem cell therapy ever help kids with trisomy?
12 doctors weighed in

Dr. James Ferguson
Pediatrics
8 doctors agree
In brief: No
With any trisomy every cell in the body has an extra chromosome in the nucleus.
That extra chromosome interferes with the normal information that tells each metabolic function how to proceed. Those trisomy's that are compatible with a rather normal life have less interference shown than others, but stem cells would never cancel or remove the extra chromosome.

In brief: No
With any trisomy every cell in the body has an extra chromosome in the nucleus.
That extra chromosome interferes with the normal information that tells each metabolic function how to proceed. Those trisomy's that are compatible with a rather normal life have less interference shown than others, but stem cells would never cancel or remove the extra chromosome.
Dr. James Ferguson
Dr. James Ferguson
Thank
1 comment
Dr. Brad Goldenberg
Actually it is possible to replace a person's stem cells with an entirely new germ line if that person received total body irradiation (TBI) and received a bone marrow transplant, has been done to cure sickle cell disease, could theoretically be done on a trisomy child, however, the effects would not reverse what morphologic changes had already happened, so for example, you couldn't reverse the intellectual disability or facial features simply by doing a bone marrow transplant on a Trisomy 21 infant
Dr. Andrew Turrisi
Radiation Oncology
1 doctor agrees
In brief: No
These are developmental abnormalities of all the somatic tissues rather than a single gene gone awry, or a simple to repair pathway only missing an enzyme.

In brief: No
These are developmental abnormalities of all the somatic tissues rather than a single gene gone awry, or a simple to repair pathway only missing an enzyme.
Dr. Andrew Turrisi
Dr. Andrew Turrisi
Thank
Get help from a real doctor now
Dr. Cindy Juster
Board Certified, Pediatrics
32 years in practice
2M people helped
Continue
108,000 doctors available
Read more answers from doctors