Explain hypoxia vs hypoxemia?

Tissues vs. blood. Hypoxia is low oxygen in the tissues. Hypoxemia is low oxygen in the arterial blood. Hypoxemia caused by low oxygen in air (such as high altitude), low ventilation (slow breathing oversedation), lung disease or blood clots in lung. Low oxygen in arterial blood leads to low oxygen in tissues but hypoxia can also be due to anemia (less oxygen carrying capacity by blood), carbon monoxide poisoning.