What works better for Parkinson's disease: levodopa or anticholinergic?

Answer. Clearly the anticholinergics are archaic, and have substantial tolerance issues. The main neurotransmitter issue involves dopamine, so L-Dopa is the most direct and logical intervention. I never use anticholinergics for my patients these days.

Related Questions

Any ways to prevent shaking taking levodopa (l-dopa) for Parkinson's disease?

Tremor in PD. A resting tremor is present in a little more than half of patients with parkinson's disease. When tremor is present, it can be treated with Levodopa medication but is often more responsive to anticholinergic medications. You can learn more about the management of parkinson's symptoms at: http://www.Pdf.Org/en/about_pd i would suggest you consult your neurologist. Read more...
I think you mean.... I suspect you mean you're on l-dopa, but you're still having tremor. Don't just add more sinemet--instead add Azilect (rasagiline) to boost your natural Dopamine and the Dopamine you get from l-dopa! this helps more fully and consistently suppress tremor, slowness & stiffness! another option would be adding amantidine to l-dopa. This often improves incomplete tremor relief by l-dopa thru glutamate antagonism. Read more...

Do you know any ways to prevent vomitting after taking levodopa (l-dopa) for Parkinson's disease?

Adding Carbidopa. Sinemet (carbidopa and levodopa) will help as Carbidopa also block GI side effects of L-Dopa. Read more...
See your neurologist. Carbidopa is usually coadministered with levodopa to increase the effective half-life of levodopa. This allows less levodopa to be required, which in turn reduces the nausea/vomiting side effects. Be sure to schedule an appointment with your neurologist in order to review your medications for Parkinson's disease. More information: http://www.nlm.nih.gov/medlineplus/druginfo/meds/a601068.html. Read more...

What is the recommended amount of sinemet (carbidopa and levodopa) to be taken for Parkinson's disease?

Sinemet (carbidopa and levodopa) Sinemet (carbidopa and levodopa) is the most effective medication in the treatment of motor symptoms of pd. Dose varies from patient to patient. Is not usually my first line of therapy in young patients unless all other options have failed. Typically start on 25/100 three times a day and adjust depending on patient's needs and response. I have few patients on only 1/2 pill twice a day and many more on 16 pills a day. Read more...

What can you do if taking levodopa (l-dopa) for Parkinson's disease causes nausea and vomiting?

Comments. 1. You are rather young at age 34 to have developed Parkinson's disease. Do you perhaps have a different diagnosis to explain your symptoms? 2. L-DOPA could cause GI side effects, and other meds may be tolerated better, BUT, 3. I recommend a second opinion from a neurologist who specializes in movement disorders at Univ of Pittsburgh. Read more...