What are the differences between autosomal dominant and autosomal recessive polycystic kidney disease?

Differences. Main differences are---ADPKD shows itself in adults and 1/3 stays silent, 1/3 cause complications like hypertension etc, and 1/3 progress to end stage renal disease. ARPKD --- on the other hand manifests itself in pediatric population, in fact soon after birth, almost always involves kidneys bilaterally and requires dialysis for survival. Good news-- ADPKD is dominant therefore never skips generat.

Related Questions

Please help! What is the difference between autosomal dominant and autosomal recessive polycystic kidney disease?

Genes. There are caused by different loci. The recessive form generally causes illness from the time of birth due to the large, ineffective kidneys. The dominant form sneaks up on a person during adult life. The affected kidneys look different in the two diseases. Read more...
See answer. Adpkd: one of most common life-threatening genetic diseases; affects ~1 in 500; does not skip a generation; usually a family history of adpkd; parents with adpkd have a 50 percent chance of passing disease on to each of their children.?? arpkd: relatively rare genetic disorder; affects ~1 in 20, 000; parents carry gene but unaffected; often causes significant mortality in the first month of life. Read more...

Is there a difference between autosomal dominant and autosomal recessive polycystic kidney disease?

Yes. The dominant form occurs mostly in adults. It is inherited but it takes time to show up as a diagnosable disease in middle to later age. Depending on your luck you either have it from your parent or not( 50% chance).The recessive form could be carried by seemingly healthy persons and when manifests as a disease in the offspring, it shows up at a much earlier age. Read more...

Is autosomal recessive polycystic kidney disease very serious?

It is different. It usually is more serious than the autosomal dominant disease since it needs inheritance from both parents to be expressed i.e. Both genes are affected. It accordingly gets expressed at an earlier age in life. The longer duration of polycystic disease is a factor in predicting dialysis need. Read more...
Cystic kidney. yes. autosomal recessive kidney disease appears early in childhood and replaces kidneys with small cysts and scar. Kidney failure appears early. Read more...

Does autosomal recessive polycystic kidney disease of one parent could be genetically transmissible to one of the children and what is the percentage?

Can transmit. For a recessive disorder you need an abnormal gene from each parent. The parent without arpckd may have one abnormal gene but has one normal one. This is called being a "carrier". The parent with arpckd has 2 abnormal genes. If the parent without the disease is a carrier, there is a 50% chance that the child will have arpckd. If the parent is not a carrier, there is a 0% chance. Read more...
ARPKD. Autosomal recessive kidney disease will transmit to a child from a parent who has ARPKD only if both parents carry the trait. Percentage is low. Read more...

Is autosomal dominant polycystic kidney disease testing available?

Yes. You have to get a renal ultrasound. It is an imaging test that determines the size and number of cysts ona kidney. Based upon the number of cysts on each kidney and depending on your age, then it can be determined if you have adpkd. Read more...
Yes, but...... Testing for this disease is safe and simple but beware of what you ask for. Knowing that you have polycystic kidney disease will make it difficult or expensive to obtain life and health insurance. Best to get these issues under control first as early diagnosis (before renal insufficiency) offers no benefit. Knowing that you have the gene prior to having children is useful for family planning. Read more...

Autosomal dominant polycystic kidney disease testing involves what kinds of tests?

See below. The current diagnostic criteria to detect cyst in the kidney is by ultrasound, however this is not a 100% accurate way as very small cysts can be missed. Ct scan can detect cysts which are smaller like 1 mm.There are no diagnostic criteria dveloped for ct scan yet. In case a young kidney donor wants to donote, but make sure he/she doesnot have the disease, there are genetic tests available. Read more...

Could autosomal dominent polycystic kidney disease be an inherited disease?

Yes. As the name implies, "autosomal dominant" indicates genetic pattern of spread to children. In this case, the affected person need only pass one of two genes to his/her child for them to be affected wight he condition. Read more...