Supportive. Mitochondria are little workshops in each cell that do work outsourced from the central nucleus. When the mitochondria do work that is defective, the intricate work of sustaining the bodies metabolism begins to fail. Over time sensitive functions decline and the person looses capabilities. After diagnosis, the aim of therapy is to preserve quality of life as long as possible.
Depend. It depend on diagnosis.
No cure yet. There is no curative treatment yet available for mitochondrial disorders. However, a lot of research is being done in this area. In the meantime, the treatment includes various supplements (vitamins and antioxidants) that may help some patients, maintaining healthy lifestyle, and avoiding triggers that may make disease worse such as certain medications that affect mitochondrial function.
Avoid toxic foods. Avoid sugars, fried foods, vegatable oils like canola & soy, meats that are cured wth nitrates & nitrites, aspartame, splenda, partially hydrogenated vegetable oils, maragarine, soy based products, sweetened beverages like juice & soda, microwaved foods, artificial colors & flavors. All of these products cause damage to the cells, tissues & organs in your body contributing to various diseases.
Maternal. One of the most distinctive features of mitochondrial dna is that of maternal inheritance, it is transmitted only by mother dna.
RE: Exercise Intolerance- the mitochondrial disorder. Is it possible that this and CFS could be one and the same? Any studies done to check this out?
Not likely. Easy fatigue is just one symptom of mitochondrial disease which is a rare medical condition cause by mutations in mitochondrial genes encoding enzymes involve in cellular oxidative metabolism. In contrast to chronic fatigue syndrome which is not uncommon, mitochondrial disorders are often associated with-neurological and cardiac dysfunction and abnormal muscle biopsy.
Energy loss. Mitochondria are the "engines"of each cell throughout the body. Loss of energy changes normal functions and the symptoms are many. Mitochondria have their own genes and they are inherited from the mother alone.
Defective data. Your centralized DNA works in the cell nucleus it interacts with bits of DNA passed down only by the mother in mitochondria (little workshops scattered around in the cell). When the DNA in the mitochondria is not working as a team with the main DNA, important work is defective. Symptoms like slow deterioration of the nervous system are a potential effect.
Chronic fatigue. Mitochondria are the "engines" of the cell. They develop the energy that enables each of your 70 to 100 trilion cells to function. The symptoms are many, depending on how many mitochondria in each cell are genetically affected.
Energy production. Defect. Small organelles in the cells responsible for generation of energy required for metabolism may malfunction due to mutations in the genes. The most common manifestation involves abnormality in the function of the muscles, other systems may be affected depending on the type of mutation.
Look online. Since mitochondrial disorders are still considered rare disease entities, support groups at a local level would be very dificult to find. I suggest you go online to some of the big centers in the us who deal with the diagnosis and treatment of these disorders (ie. Children's hospital of philidelphia, cleveland clinic) and see if they have online support groups and parental geoups.
No. Treacher collins syndrome is an autosomal dominant mutation of a gene that codes for a nucleolar phosphoprotein. Researchers cite chromasome 5 as the predominant location for this defect. About 60% of cases are thought to represent new mutations.