What is the treatment for lovenox (enoxaparin) overdose?

Lovenox (enoxaparin) overdose. Lovenox (enoxaparin) overdoses can be treated by holding the medication, giving an antidote called protamine, transfusing blood products as needed, and using agents to promote blood clotting (anti-fibrinolytic agents, recombinant factor fvii, etc.).
Protamine. Overdose of Lovenox may lead to bleeding, so it is important to manage this medication properly. The antidote for an overdose is protamine and the dose depends on the amount of lovenox administered and the time since administration. Protamine reverses Lovenox. In all cases, Lovenox be stopped until there is no longer a risk for significant bleeding.