What is the treatment for hypereosinophilic syndrome?

Typically prednisone. Prednisone or other corticosteroids are very effective at controlling eosinophil levels and are usually the first line of treatment. Do to the long-term side effects, other medications like Hydroxyurea and interferon-alpha can be used to lower the doses of steroids that are required. If the syndrome is related to a leukemia or a specific dna mutation, treatment with chemotherapy may be effective.